Open federal opportunity · PAR-28-056

Pancreatic Cancer Detection Consortium: Research Units (U01 Clinical Trial Optional)

National Institutes of Health lists this opportunity for nonprofit applicant type listed. Review the coded eligibility, award range, source synopsis, and official notice before deciding whether to apply.

Health

Deadline

November 5, 2029

1111 days remaining

Award range

up to $600,000

official range may be incomplete

Applicant signal

Nonprofit applicant type listed

the official notice controls eligibility

Official synopsis

Through this Notice of Funding Opportunity (NOFO), NCI solicits applications for the Research Units (RUs), one of the two scientific components of the Pancreatic Cancer Detection Consortium (PCDC), to conduct research on early detection of pancreatic ductal adenocarcinoma (PDAC) and characterization of its precursor lesions to identify patients who are at high risk of progression to cancer. The PCDC will continue to address one of the four research priorities identified in the NCI's 2014 Scientific Framework for Pancreatic Ductal Adenocarcinoma (PDAC). The PCDC will support research for the development and testing of new molecular and imaging biomarkers for detecting PDAC early and for identifying patients at high risk of PDAC (because of genetic factors, family history and/or the presence of precursor lesions) who could be candidates for early intervention. The PCDC-RUs will consist of multi-disciplinary teams and will undertake studies to: identify and test biomarkers measurable in bodily fluids for early detection of PDAC and/or its precursor lesions; develop molecular- and/or imaging-based markers of pancreatic cysts and determine which lesions are likely to progress to cancer; develop molecular- and/or imaging-based approaches for screening populations at high risk of PDAC; use machine learning and computational approaches towards biomarker discovery and/or validation; and conduct biomarker validation studies. The PCDC-RUs will also collect longitudinal biospecimens for building a biorepository. Each PCDC-RU is expected to participate in collaborative activities with other PCDC-RUs and share ideas, biospecimens, and data within the Consortium.

Open the official Grants.gov listing ↗

Coded applicant types
  • 00 — State governments
  • 01 — County governments
  • 02 — City or township governments
  • 04 — Special district governments
  • 05 — Independent school districts
  • 06 — Public and state-controlled institutions of higher education
  • 07 — Federally recognized Native American tribal governments
  • 08 — Public housing authorities and Indian housing authorities
  • 11 — Native American tribal organizations other than federally recognized tribal governments
  • 12 — 501(c)(3) nonprofits other than institutions of higher education
  • 13 — Nonprofits without 501(c)(3) status other than institutions of higher education
  • 20 — Private institutions of higher education
  • 22 — For-profit organizations other than small businesses
  • 23 — Small businesses
  • 25 — Other applicants; see the official eligibility clarification

These are high-level Grants.gov codes. Additional eligibility text, geographic restrictions, and program-specific rules in the official notice can narrow them.

Before investing application time
  1. Confirm entity eligibility in the full Notice of Funding Opportunity.
  2. Check SAM.gov and Grants.gov registration requirements and timing.
  3. Read every attachment for matching, cost-share, geography, and award conditions.
  4. Verify the exact deadline time and any agency-specific submission portal.
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Source: Grants.gov daily XML extract, 2026-10-21 extract. This page reproduces selected public listing fields for research convenience. The official Notice of Funding Opportunity and agency instructions control. This product uses the Grants.gov API but is not endorsed or certified by the U.S. Department of Health and Human Services.