Open federal opportunity · PAR-26-042

Research Grants in Clinical Informatics (R01 Clinical Trial Optional)

National Institutes of Health lists this opportunity for nonprofit applicant type listed. Review the coded eligibility, award range, source synopsis, and official notice before deciding whether to apply.

Health

Deadline

March 5, 2029

866 days remaining

Award range

up to $250,000

$2,500,000 estimated program funding

Applicant signal

Nonprofit applicant type listed

the official notice controls eligibility

Official synopsis

The National Library of Medicine (NLM) seeks applications for innovative research in clinical informatics. The overarching goal of this forthcoming program is to catalyze the development and advancement of novel informatics methodologies that empower clinicians, patients, and the broader public to better understand, manage, and improve health and health care delivery. This NOFO will support research focused on the design, implementation, and evaluation of clinical informatics tools and methods that enable data-driven discovery, promote evidence-based decision-making, and support personalized and precision health care. Emphasis will be placed on domain-independent, scalable, and reusable/reproducible approaches for the discovery, analysis, organization, and management of health-related digital objects—including electronic health records (EHRs), clinical notes, imaging data, and patient-generated data. The aim is to transform raw and heterogeneous health data into actionable knowledge, to develop innovative tools, and to implement practical applications that can be generalized across multiple clinical settings and populations. Projects should demonstrate the potential to accelerate scientific insights, improve clinical workflows, and ultimately lead to improved health outcomes.

Open the official Grants.gov listing ↗

Coded applicant types
  • 00 — State governments
  • 01 — County governments
  • 02 — City or township governments
  • 04 — Special district governments
  • 05 — Independent school districts
  • 06 — Public and state-controlled institutions of higher education
  • 07 — Federally recognized Native American tribal governments
  • 08 — Public housing authorities and Indian housing authorities
  • 11 — Native American tribal organizations other than federally recognized tribal governments
  • 12 — 501(c)(3) nonprofits other than institutions of higher education
  • 13 — Nonprofits without 501(c)(3) status other than institutions of higher education
  • 20 — Private institutions of higher education
  • 22 — For-profit organizations other than small businesses
  • 23 — Small businesses
  • 25 — Other applicants; see the official eligibility clarification

These are high-level Grants.gov codes. Additional eligibility text, geographic restrictions, and program-specific rules in the official notice can narrow them.

Before investing application time
  1. Confirm entity eligibility in the full Notice of Funding Opportunity.
  2. Check SAM.gov and Grants.gov registration requirements and timing.
  3. Read every attachment for matching, cost-share, geography, and award conditions.
  4. Verify the exact deadline time and any agency-specific submission portal.
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Source: Grants.gov daily XML extract, 2026-10-21 extract. This page reproduces selected public listing fields for research convenience. The official Notice of Funding Opportunity and agency instructions control. This product uses the Grants.gov API but is not endorsed or certified by the U.S. Department of Health and Human Services.