This Notice of Funding Opportunity (NOFO) announces the restructured Shared Instrumentation Grant (SIG) Program that consolidates three existing shared-use instrumentation programs, i.e., the Shared Instrumentation Grant program, the High-End Instrumentation Grant program, and the Basic Instrumentation Grant program. The NOFO invites applications from groups of NIH-supported investigators to purchase or upgrade a single state-of-the-art commercially available instrument or an integrated instrumentation system. The instruments purchased through the SIG Program are required to be optimally shared among the users to ensure efficient and cost-effective research operations, enable rigorous and reproducible measurements, and encourage collaborative research and benefit broad research communities at large. The minimum award is $300,000. There is no cap on the total cost of the instrument; however, the maximum award is $5,000,000. Cost sharing is required for premium instruments or special use instruments.
Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)
National Institutes of Health lists this opportunity for nonprofit applicant type listed. Review the coded eligibility, award range, source synopsis, and official notice before deciding whether to apply.
Deadline
July 1, 2028
619 days remaining
Award range
$300,000–$5,000,000
official range may be incomplete
Applicant signal
Nonprofit applicant type listed
the official notice controls eligibility
- 00 — State governments
- 01 — County governments
- 02 — City or township governments
- 04 — Special district governments
- 05 — Independent school districts
- 06 — Public and state-controlled institutions of higher education
- 07 — Federally recognized Native American tribal governments
- 08 — Public housing authorities and Indian housing authorities
- 11 — Native American tribal organizations other than federally recognized tribal governments
- 12 — 501(c)(3) nonprofits other than institutions of higher education
- 13 — Nonprofits without 501(c)(3) status other than institutions of higher education
- 20 — Private institutions of higher education
- 22 — For-profit organizations other than small businesses
- 23 — Small businesses
- 25 — Other applicants; see the official eligibility clarification
These are high-level Grants.gov codes. Additional eligibility text, geographic restrictions, and program-specific rules in the official notice can narrow them.
- Confirm entity eligibility in the full Notice of Funding Opportunity.
- Check SAM.gov and Grants.gov registration requirements and timing.
- Read every attachment for matching, cost-share, geography, and award conditions.
- Verify the exact deadline time and any agency-specific submission portal.
Want the opportunities that fit your work?
FunderFit compares your program with live federal opportunities and application-ready foundations, then delivers a ranked, source-labeled shortlist.
Source: Grants.gov daily XML extract, 2026-10-21 extract. This page reproduces selected public listing fields for research convenience. The official Notice of Funding Opportunity and agency instructions control. This product uses the Grants.gov API but is not endorsed or certified by the U.S. Department of Health and Human Services.